2009Zhongguo shiyong neike zazhiRequires access

Diseases which should be differentiated from motor neuron disease

LU Jia-hon

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Abstract

Motor neuron disease(MND)is a kind of degenerating disease which involves the upper and lower motor neurons.Irreversible muscle weakness,muscle atrophy and pyramidal sign are its main clinical manifestations.Diagnosis of MND should be made with caution because no effective treatment can change the unceasing course.This article specifies the diseases which mimic MND:cervical spondylosis,Hirayama disease,multifocal motor neuropathy,monoclonal gammopathy with motor neuropathy,paraneoplastic motor neuron syndrome,post-polio syndrome,spinal muscular atrophy,Kennedy syndrome and diabetic amyotrophy.Wish it do some favor to clinical doctors.

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What this paper is about

Motor neuron disease(MND)is a kind of degenerating disease which involves the upper and lower motor neurons.Irreversible muscle weakness,muscle atrophy and pyramidal sign are its main clinical manifestations.Diagnosis of MND should be made with caution because no effective treatment can change the unceasing course.This article specifies the diseases which mimic MND:cervical spondylosis,Hirayama disease,multifocal motor neuropathy,monoclonal gammopathy with motor neuropathy,paraneoplastic motor neuron syndrome,post-polio syndrome,spinal muscular atrophy,Kennedy syndrome and diabetic amyotrophy.Wish it do some favor to clinical doctors.

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Available abstract

Motor neuron disease(MND)is a kind of degenerating disease which involves the upper and lower motor neurons.Irreversible muscle weakness,muscle atrophy and pyramidal sign are its main clinical manifestations.Diagnosis of MND should be made with caution because no effective treatment can change the unceasing course.This article specifies the diseases which mimic MND:cervical spondylosis,Hirayama disease,multifocal motor neuropathy,monoclonal gammopathy with motor neuropathy,paraneoplastic motor neuron syndrome,post-polio syndrome,spinal muscular atrophy,Kennedy syndrome and diabetic amyotrophy.Wish it do some favor to clinical doctors.

Key concepts: Motor neuron, Medicine, Amyotrophy, Amyotrophic lateral sclerosis, Lower motor neuron, Cervical spondylosis, Multifocal motor neuropathy, Progressive muscular atrophy

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