Efficacy of Intramammary Extended Therapy Using Ceftiofur (Spectramast® LC) against Clinical Mastitis of Holstein Cows

Little research has focused on extended therapy for cows with clinical mastitis during lactation. Ceftiofur should be effective against a wide range of mastitis pathogens including gram-positive and gram-negative bacteria. It could be considered as a reasonable choice for treatment of clinical mastitis. The objective of the present study was to determine if extended therapy would increase cure rates of a ceftiofur treatment for non-acute clinical mastitis, for all bacteria and more specifically for Staphylococcus aureus and streptococci. The hypothesis was that extended therapy would enhance the cure rate of ceftiofur for non-acute clinical mastitis.