Masahiko Seki, Yusuke Takahashi
Abstract
Abstract A highly practical procedure for the preparation of bromoanilines by using copper-catalyzed oxidative bromination has been developed. Treatment of free anilines with readily available NaBr and Na2S2O8 in the presence of a catalytic amount of CuSO4·5H2O enabled regioselective bromination.
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Abstract A highly practical procedure for the preparation of bromoanilines by using copper-catalyzed oxidative bromination has been developed. Treatment of free anilines with readily available NaBr and Na2S2O8 in the presence of a catalytic amount of CuSO4·5H2O enabled regioselective bromination.
Key concepts: Halogenation, Regioselectivity, Chemistry, Catalysis, Organic chemistry, Oxidative phosphorylation, Combinatorial chemistry, Biochemistry