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2015•Faṣlnāmah-i bīmārīhā-yi pūstRequires access

Serum protein carbonyl and total antioxidant capacity levels in pemphigus vulgaris and bullous pemphigoid

Ahmad Reza Taheri, Tanipour Mohammad Hossein, Khorasani Zahra Kafami, Bita Kiafar, Pouran Layegh, Seyed Isaac Hashemy

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Abstract

Background: Pemphigus diseases including pemphigus vulgaris (PV) and bullous pemphigoid (BP) are autoimmune diseases that cause severe blistering of the skin and mucous membranes. Among inflammatory mediators, reactive oxygen species (ROS) are involved in the pathogenesis of a wide variety of diseases through oxidative stress for which protein carbonyl (PC) and total antioxidant capacity (TAC) are two important markers.Methods: We utilized PC and TAC in this study to compare the serum redox status of PV and BP patients with healthy subjects to investigate the possible ro

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Background: Pemphigus diseases including pemphigus vulgaris (PV) and bullous pemphigoid (BP) are autoimmune diseases that cause severe blistering of the skin and mucous membranes. Among inflammatory mediators, reactive oxygen species (ROS) are involved in the pathogenesis of a wide variety of diseases through oxidative stress for which protein carbonyl (PC) and total antioxidant capacity (TAC) are two important markers.Methods: We utilized PC and TAC in this study to compare the serum redox status of PV and BP patients with healthy subjects to investigate the possible ro

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Available abstract

Background: Pemphigus diseases including pemphigus vulgaris (PV) and bullous pemphigoid (BP) are autoimmune diseases that cause severe blistering of the skin and mucous membranes. Among inflammatory mediators, reactive oxygen species (ROS) are involved in the pathogenesis of a wide variety of diseases through oxidative stress for which protein carbonyl (PC) and total antioxidant capacity (TAC) are two important markers.Methods: We utilized PC and TAC in this study to compare the serum redox status of PV and BP patients with healthy subjects to investigate the possible ro

Key concepts: Pemphigus vulgaris, Bullous pemphigoid, Pemphigus, Pemphigoid, Antioxidant capacity, Antioxidant, Medicine, Oxidative stress

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