2003Unpublished venueOpen access

The pathogenesis of diabetic nephropathy

Richard E. Gilbert, Mark Emmanuel Cooper

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Abstract

The pathogenesis of diabetic nephropathy is incompletely understood, but is likely to involve interactions among cells, growth factors, structural proteins and cell receptors for these molecules. Recent advances in cellular and molecular biology have highlighted the complex nature of these molecular interactions (Fig. 11.1), but have also brought significant advances in providing a pathophysiological basis for prevention and therapeutic intervention in diabetic nephropathy.

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The pathogenesis of diabetic nephropathy is incompletely understood, but is likely to involve interactions among cells, growth factors, structural proteins and cell receptors for these molecules. Recent advances in cellular and molecular biology have highlighted the complex nature of these molecular interactions (Fig. 11.1), but have also brought significant advances in providing a pathophysiological basis for prevention and therapeutic intervention in diabetic nephropathy.

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Available abstract

The pathogenesis of diabetic nephropathy is incompletely understood, but is likely to involve interactions among cells, growth factors, structural proteins and cell receptors for these molecules. Recent advances in cellular and molecular biology have highlighted the complex nature of these molecular interactions (Fig. 11.1), but have also brought significant advances in providing a pathophysiological basis for prevention and therapeutic intervention in diabetic nephropathy.

Key concepts: Pathogenesis, Diabetic nephropathy, Medicine, Nephropathy, Diabetes mellitus, Internal medicine, Endocrinology

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