2020Russian otorhinolaryngologyOpen access

Case report of chondrosarcoma of the larynx

Aleksandr Makhonin, T. Yu. Vladimirova, A. G. Gabrielyan, A. I. Sinotin, Yu. G. Bakanova, M. S. Belyanina, K. А. Ganina

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Abstract

The chondrosarcoma of the larynx is a poorly understood and rare malignant tumour. It accounts for only 1% of malignant neoplastic pathology of the larynx, but at the same time it is the most common non-epithelial neoplasm of the larynx. More often occurs in the area of the cricoid cartilage, namely the inner plate, less often in the area of the vocal folds and the epiglottis. There are no clinical guidelines for the treatment of chondrosarcoma of the larynx, therefore each clinical case describing clinical observations of this rare tumour is of interest. A clinical case of chondrosarcoma of the larynx is presented in a 55-year-old man who complained of hoarseness for 3 months. The patient underwent a complete clinical and instrumental examination, but computed tomography (CT) is of the greatest value. According to CT data, a calcified mass is visualized in the cricoid cartilage. At the first stage, the patient underwent resection of the cricoid cartilage in order to verify the diagnosis. Histological examination: low-grade chondrosarcoma. At the second stage, a radical surgical treatment was performed - laryngectomy. 8 months after the operation, the patient has no data on the relapse and progression of the disease according to the survey data. Currently, total laryngectomy is preferred for patients with recurrent low-grade chondrosarcoma. However, a literature review and our case show that the inability to restore the cricoid cartilage of the larynx, which is affected in most cases, often leads to laryngectomy

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The chondrosarcoma of the larynx is a poorly understood and rare malignant tumour. It accounts for only 1% of malignant neoplastic pathology of the larynx, but at the same time it is the most common non-epithelial neoplasm of the larynx. More often occurs in the area of the cricoid cartilage, namely the inner plate, less often in the area of the vocal folds and the epiglottis. There are no clinical guidelines for the treatment of chondrosarcoma of the larynx, therefore each clinical case describing clinical observations of this rare tumour is of interest. A clinical case of chondrosarcoma of the larynx is presented in a 55-year-old man who complained of hoarseness for 3 months. The patient underwent a complete clinical and instrumental examination, but computed tomography (CT) is of the greatest value. According to CT data, a calcified mass is visualized in the cricoid cartilage. At the first stage, the patient underwent resection of the cricoid cartilage in order to verify the diagnosis. Histological examination: low-grade chondrosarcoma. At the second stage, a radical surgical treatment was performed - laryngectomy. 8 months after the operation, the patient has no data on the relapse and progression of the disease according to the survey data. Currently, total laryngectomy is preferred for patients with recurrent low-grade chondrosarcoma. However, a literature review and our case show that the inability to restore the cricoid cartilage of the larynx, which is affected in most cases, often leads to laryngectomy

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Available abstract

The chondrosarcoma of the larynx is a poorly understood and rare malignant tumour. It accounts for only 1% of malignant neoplastic pathology of the larynx, but at the same time it is the most common non-epithelial neoplasm of the larynx. More often occurs in the area of the cricoid cartilage, namely the inner plate, less often in the area of the vocal folds and the epiglottis. There are no clinical guidelines for the treatment of chondrosarcoma of the larynx, therefore each clinical case describing clinical observations of this rare tumour is of interest. A clinical case of chondrosarcoma of the larynx is presented in a 55-year-old man who complained of hoarseness for 3 months. The patient underwent a complete clinical and instrumental examination, but computed tomography (CT) is of the greatest value. According to CT data, a calcified mass is visualized in the cricoid cartilage. At the first stage, the patient underwent resection of the cricoid cartilage in order to verify the diagnosis. Histological examination: low-grade chondrosarcoma. At the second stage, a radical surgical treatment was performed - laryngectomy. 8 months after the operation, the patient has no data on the relapse and progression of the disease according to the survey data. Currently, total laryngectomy is preferred for patients with recurrent low-grade chondrosarcoma. However, a literature review and our case show that the inability to restore the cricoid cartilage of the larynx, which is affected in most cases, often leads to laryngectomy

Key concepts: Larynx, Cricoid cartilage, Chondrosarcoma, Laryngectomy, Medicine, Epiglottis, Radiology, Thyroid cartilage

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