2021•New Journal of ChemistryRequires access

Rhodium( i ) N-heterocyclic carbene complexes: synthesis and cytotoxic properties

Ichraf Slimani, Serap Şahin‐Bölükbaşı, Mustafa Ulu, Enes Evren, Nevın Gürbüz, İlknur Özdemir, İlknur Özdemir, Naceur Hamdi, İsmaıl Özdemır, İsmaıl Özdemır

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Abstract

A series of benzimidazolium salts and their [RhCl(NHC)(COD)] complexes were synthesized. All compounds were screened for in vitro cytotoxic activities against a panel of human cancer cells (HT-29 colon, Ishikawa endometrial, U-87 glioblastoma) using the MTT assay for 48 h incubation time.

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Key concepts: Chemistry, Cytotoxic T cell, Rhodium, Carbene, In vitro, MTT assay, Cytotoxicity, Stereochemistry