2021•Journal of VirologyOpen access

Porcine Complement Regulatory Protein CD46 Is a Major Receptor for Atypical Porcine Pestivirus but Not for Classical Swine Fever Virus

Gökce Nur Cagatay, Aleksandra Antos, Oliver Suckstorff, Olaf Isken, Norbert Tautz, Paul Becher, Alexander Postel

Abstract

Pestiviruses comprise animal pathogens such as classical swine fever virus (CSFV) and bovine viral diarrhea virus (BVDV) that cause notifiable diseases with great economic impact. Several additional pestivirus species affecting animal health were recently identified, including atypical porcine pestivirus (APPV).

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Key concepts: Biology, Pestivirus, Virology, Classical swine fever, CD46, Virus, Porcine circovirus, Flaviviridae