Acitretin for Secondary Prevention of Keratinocyte Cancers in a Veteran Population: A Retrospective Cohort Study.
Rachel Lim, Martin A. Weinstock, Shoshana Landow
Abstract
Rachel Lim, Martin A. Weinstock, Shoshana Landow
Abstract
Acitretin, a vitamin A derivative used for psoriasis, can prevent keratinocyte carcinoma (KC). It induced regression of keratoacanthomas (KA) in animal models, presumably by activating retinoic acid and retinoid X receptors that regulate gene expression for growth and proliferation.1,2.
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Acitretin, a vitamin A derivative used for psoriasis, can prevent keratinocyte carcinoma (KC). It induced regression of keratoacanthomas (KA) in animal models, presumably by activating retinoic acid and retinoid X receptors that regulate gene expression for growth and proliferation.1,2.
Key concepts: Acitretin, Medicine, Retinoid, Keratinocyte, Psoriasis, Retinoic acid, Bexarotene, Retrospective cohort study