Surgical Treatment of Female Stress Urinary Incontinence Using Injectables

Stress urinary incontinence (SUI) is a condition prevalent in adult women. Among the available treatment alternatives, minimal invasive options such as the injection of periurethral bulking agents (PBAs) remain preferable to many women because of ease of administration and very minimal postoperative morbidity. Its primary use has, however, been in the treatment of intrinsic sphincter deficiency. The quest to find the ideal agent is ongoing. Many PBAs are available, whereas some are no longer in the market. This review examines the historical aspect and indications of PBAs, the relevant surgical techniques, and current injectable agents in use and their effectiveness along with associated adverse events. This review contains 5 figures, 3 tables, and 51 references. Keywords: female, stress urinary incontinence, minimally invasive procedure, mechanism, bulking agent, intrinsic sphincter deficiency, efficacy, technique, complications