2021•Unpublished venueRequires access
Optogenetic cardiac pacing and its applications
Airong Li, Rudolph E. Tanzi
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Abstract
Optogenetics combines the biological techniques of optics and genetics and uses light to control
the activities of living tissues such as neurons and heart. Optogenetic actuators including
channelrhodopsin (ChR), halorhodopsin (NpHR), and archaerhodopsin specifically provide for
neuronal or cardiac controls. The clinical translation of cardiac optogenetics will include human
and larger mammalian animal model applications and ultimately optogenetics may have the
power to restore normal heart rhythm.