Current perceptive on canine cystic endometrial hyperplasia-pyometra syndrome-A review

Cystic endometrial hyperplasia-pyometra complex (CEH/P) is a life-threatening challenge in canine reproduction. Hormonal imbalances result in environmental and histological changes in the uterus leading to a predisposition to bacterial growth. Haematological analysis shows the total number of leucocytes is frequently elevated in cases of pyometra, although the degree is much less marked in cases of open cervix pyometra compared with closed cervix pyometra. Ovariohysterectomy is the treatment of choice for closed cervix or open cervix pyometra. If the condition is not life-threatening and the animal is enrolled in breeding programmed or particularly valuable or when the clinical situation precludes surgery, medical treatment may be considered.