Features of poisoning with nasal decongestants in young children

Relevance: Poisoning with nasal decongestants occupies a leading place among drug poisoning in children, therefore it is important to study the structure, clinical features of drug poisoning with the subsequent development of prevention methods. Purpose: to study the structure and clinical features of nasal decongestant poisoning in children of the Voronezh region. Methods: retrospective analysis of case histories of children admitted to the hospital with drug poisoning in the period 2016-2018. Results: 127 case histories of patients were analyzed, of which 73 people (57.5%) were admitted with drug poisoning. Poisoning with nasal decongestants was observed in 15 children (20.5%), mainly at the age of 1 to 3 years (86.7%). The main drug that caused the poisoning was naphazoline in 13 patients (86.7%). Intranasal route of drug intake was observed in 5 people (33.3%), oral - in 10 people (66.6%). Moderate poisoning was observed in 7 children (46.6%), severe poisoning also in 7 patients (46.6%), extremely severe poisoning in 1 child (6.6%). The oral route of administration of the drug led to a more severe course of poisoning in children (p <0.05) with the development of severe bradycardia in 9 cases (60%). Therapeutic measures included gastric lavage, infusion therapy; 1 child (6.7%) needed atropine. All children were discharged with recovery. Conclusion: analysis of the structure of poisoning in children is necessary in order to develop preventive measures to reduce their number and prevent poisoning.