STRATEGIES FOR MANAGEMENT OF ALZHEIMER’S DISEASE: A REVIEW
Ishu Sharma, Ankit Kumar
Abstract
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Ishu Sharma, Ankit Kumar
Abstract
Open-access reader
Alzheimer’s is the most widely recognized reason for dementia discovered by Alois Alzheimer’s in 1906. Severity of Alzheimer’s disease is increments with age and mostly after 65 years. It is a progressive neurodegenerative disease that damage memory and intellectual capacities. It affects 34 million people worldwide and as time goes, the pervasiveness of Alzheimer’s disease continues to increase and as indicated by WHO it can reaches to 95 million by 2050. Manifestation of Alzheimer’s incorporates cognitive decline that changes day by day way of life, trouble in finishing everyday errands, disarray with time or spot, misguide thinking. Most preferred drugs used for Alzheimer’s are cholinesterase inhibitors like Donepezil, rivastigmine, Galantamine, Tacrine, NMDA receptor antagonist like memantine. The purpose of this review article is to provide a brief introduction, potential causes, symptoms and mechanism of action of Alzheimer’s disease. This review article likewise accentuation on utilization of therapeutic plants and isolated compounds for preventing and reducing the symptoms of Alzheimer’s disease.
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Alzheimer’s is the most widely recognized reason for dementia discovered by Alois Alzheimer’s in 1906. Severity of Alzheimer’s disease is increments with age and mostly after 65 years. It is a progressive neurodegenerative disease that damage memory and intellectual capacities. It affects 34 million people worldwide and as time goes, the pervasiveness of Alzheimer’s disease continues to increase and as indicated by WHO it can reaches to 95 million by 2050. Manifestation of Alzheimer’s incorporates cognitive decline that changes day by day way of life, trouble in finishing everyday errands, disarray with time or spot, misguide thinking. Most preferred drugs used for Alzheimer’s are cholinesterase inhibitors like Donepezil, rivastigmine, Galantamine, Tacrine, NMDA receptor antagonist like memantine. The purpose of this review article is to provide a brief introduction, potential causes, symptoms and mechanism of action of Alzheimer’s disease. This review article likewise accentuation on utilization of therapeutic plants and isolated compounds for preventing and reducing the symptoms of Alzheimer’s disease.
Key concepts: Rivastigmine, Galantamine, Donepezil, Memantine, Tacrine, Disease, Dementia, Alzheimer's disease