2020•PEDIATRICSRequires access

Lenticulostriate Vasculopathy and Neurodevelopmental Outcomes in Preterm Infants: A Retrospective Cohort Study

Abby E. Robinson, John J. Flibotte, Sara B. DeMauro, Summer L. Kaplan

Abstract

Lenticulostriate vasculopathy (LSV), defined by linear echogenicities in the thalamus and basal ganglia on ultrasound, is a finding reported on 5-20% of screening cranial ultrasounds in preterm infants. However, its significance for predicting future neurodevelopmental outcomes is unclear. Purpose: Describe the incidence of LSV in a cohort of very preterm infants in one level 3 neonatal intensive care unit (NICU) and the association between this radiologic finding and 2-year neurodevelopmental outcomes. Methods: This was a retrospective cohort study of infants born at one large, urban academic institution between 1/1/2010 and …

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Key concepts: Medicine, Neonatal intensive care unit, Retrospective cohort study, Pediatrics, Cohort, Incidence (geometry), Cohort study, Internal medicine