2020•Molecular CellOpen access

Functionally distinct roles for TET-oxidized 5-methylcytosine bases in somatic reprogramming to pluripotency

Blake A. Caldwell, Monica Yun Liu, Rexxi D. Prasasya, Tong Wang, Jamie E. DeNizio, N. Adrian Leu, Nana Yaa A. Amoh, Christopher Krapp, Yemin Lan, Emily Shields, Roberto Bonasio, Christopher J. Lengner, Rahul M. Kohli, Marisa S. Bartolomei

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Key concepts: Reprogramming, DNA demethylation, 5-Hydroxymethylcytosine, Biology, Somatic cell, Chromatin, Epigenetics, Demethylation