2020PEDIATRICSRequires access

This Guillain-Barré Won’t Go Away: Chronic Inflammatory Demyelinating Polyneuropathy in an 18-year-old male

Julia Ding, Michael Köster

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Abstract

Introduction: Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is a rare diagnosis, encompassing a group of related neuropathies that share the characteristics of chronicity, demyelination, inflammation, and immune-mediation. It exists along a temporal continuum with its acute counterpart: the demyelinating form of Guillain-Barre Syndrome (GBS), a monophasic illness which typically resolves in the span of weeks. First line treatments of CIDP include corticosteroids, intravenous immunoglobulin (IVIG), and plasma exchange, although more aggressive presentations may require additional immunotherapy. We present a case of CIDP in an adolescent patient. As a disease …

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Introduction: Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is a rare diagnosis, encompassing a group of related neuropathies that share the characteristics of chronicity, demyelination, inflammation, and immune-mediation. It exists along a temporal continuum with its acute counterpart: the demyelinating form of Guillain-Barre Syndrome (GBS), a monophasic illness which typically resolves in the span of weeks. First line treatments of CIDP include corticosteroids, intravenous immunoglobulin (IVIG), and plasma exchange, although more aggressive presentations may require additional immunotherapy. We present a case of CIDP in an adolescent patient. As a disease …

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Available abstract

Introduction: Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is a rare diagnosis, encompassing a group of related neuropathies that share the characteristics of chronicity, demyelination, inflammation, and immune-mediation. It exists along a temporal continuum with its acute counterpart: the demyelinating form of Guillain-Barre Syndrome (GBS), a monophasic illness which typically resolves in the span of weeks. First line treatments of CIDP include corticosteroids, intravenous immunoglobulin (IVIG), and plasma exchange, although more aggressive presentations may require additional immunotherapy. We present a case of CIDP in an adolescent patient. As a disease …

Key concepts: Medicine, Chronic inflammatory demyelinating polyneuropathy, Guillain-Barre syndrome, Immunology, Polyradiculoneuropathy, Polyneuropathy, Antibody, Pediatrics

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