Granulocyte colony-stimulating factor – why it is worth to use filgrastim?
Natalia Ścirka, Tomasz Kubiatowski
Abstract
Natalia Ścirka, Tomasz Kubiatowski
Abstract
Neutropenia fever is one of the most common side effect of chemotherapy and might lead to severe complications and death. The use of granulocyte colony-stimulating factors in primary and secondary prevention of neutropenia fever leads to reduction in hospitalization time and significantly affects the decrease in treatment-related mortality. Factors stimulating granulocyte colonies prevent the need to reduce the dose of the cytostatics and to extend the intervals between the treatment cycles, which increases the effectiveness of therapy.
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Neutropenia fever is one of the most common side effect of chemotherapy and might lead to severe complications and death. The use of granulocyte colony-stimulating factors in primary and secondary prevention of neutropenia fever leads to reduction in hospitalization time and significantly affects the decrease in treatment-related mortality. Factors stimulating granulocyte colonies prevent the need to reduce the dose of the cytostatics and to extend the intervals between the treatment cycles, which increases the effectiveness of therapy.
Key concepts: Filgrastim, Neutropenia, Granulocyte colony-stimulating factor, Medicine, Granulocyte, Chemotherapy, Intensive care medicine, Internal medicine