Frequent Versus Infrequent Bathing in Pediatric Atopic Dermatitis: A Randomized Clinical Trial

Advertising Disclaimer » Main menu JournalsPediatrics Hospital Pediatrics Pediatrics in Review NeoReviews AAP Grand Rounds AAP News Authors/ReviewersSubmit Manuscript Author Guidelines Reviewer Guidelines Open Access Editorial Policies ContentCurrent Issue Online First Archive Blogs Topic/Program Collections AAP Meeting Abstracts Pediatric CollectionsCOVID-19 Racism and Its Effects on Pediatric Health More Collections... AAP Policy SupplementsSupplements Publish Supplement MultimediaVideo Abstracts Pediatrics On Call Podcast Subscribe Alerts Careers Other PublicationsAmerican Academy of Pediatrics User menu Log in My Cart Search Source All JournalsAAP NewsAAP Grand RoundsHospital PediatricsNeoReviewsPediatricsPediatrics in Review Search for this keyword Advanced search Source All JournalsAAP NewsAAP Grand RoundsHospital PediatricsNeoReviewsPediatricsPediatrics in Review Search for this keyword Advanced Search Log in My Cart JournalsPediatrics Hospital Pediatrics Pediatrics in Review NeoReviews AAP Grand Rounds AAP News Authors/ReviewersSubmit Manuscript Author Guidelines Reviewer Guidelines Open Access Editorial Policies ContentCurrent Issue Online First Archive Blogs Topic/Program Collections AAP Meeting Abstracts Pediatric CollectionsCOVID-19 Racism and Its Effects on Pediatric Health More Collections... AAP Policy SupplementsSupplements Publish Supplement MultimediaVideo Abstracts Pediatrics On Call Podcast Subscribe Alerts Careers We will not be accepting article comments until November 8, 2021, while our site undergoes major changes. We apologize for the inconvenience. For questions, contact the editorial office. Allergy Frequent Versus Infrequent Bathing in Pediatric Atopic Dermatitis: A Randomized Clinical Trial Joseph M. Damron and Marcus Shaker Pediatrics December 2020, 146 (Supplement 4) S340; DOI: https://doi.org/10.1542/peds.2020-023861FF Joseph M. Damron Lebanon, New HampshireFind this author on Google ScholarFind this author on PubMedSearch for this author on this siteMarcus Shaker Lebanon, New HampshireFind this author on Google ScholarFind this author on PubMedSearch for this author on this site ArticleInfo & MetricsComments Download PDF ID Cardona, EE Kempe, C Lary, JH Ginder, N Jain. J Allergy Clin Immunol Pract. 2020;8(3):1014–1021PURPOSE OF THE STUDY:To examine the relationship between bathing frequency and disease severity in pediatric atopic dermatitis (AD).STUDY POPULATION:The study included 42 children aged 6 months to 11 years with moderate-to-severe AD.METHODS:The authors conducted a 1:1 randomized, single-blind, crossover trial over a two-week period comparing twice-daily soak-and-seal bathing 15 to 20 minutes (“wet method”) with twice-weekly soak-and-seal bathing less than 10 minutes (“dry method”). Patients received the same treatment of a moisturizer, cleanser, and low-potency topical corticosteroid. The primary end point was change in physician-scored disease using the SCORing Atopic Dermatitis (SCORAD) index, and secondary end points included caregiver assessment of disease severity, quality of life indices, bacterial colonization, and skin hydration status. Analysis of efficacy was per intent to treat with all patients who were randomized.RESULTS:Of the population screened, two-thirds met the inclusion criteria, and only 5% were lost to follow-up. Twice-daily soak and seal decreased severity index by 21.2 (95% CI, 14.9–27.6, P < .0001) compared with twice-weekly bathing (greater than the minimal clinically important difference of 8.7). Fifty-eight percent of children receiving the wet method had a greater than 30% physician-assessed SCORAD improvement; however, a subset of patients (15%) did achieve a greater response with the “dry method.” Parent-assessed severity also improved significantly for the wet method compared with the dry method (P = .0052). No significant differences in quality of life indices, skin hydration status, S aureus relative colonization density, or desonide usage were observed.CONCLUSIONS:Twice-daily soak-and-seal bathing is an effective strategy for moderate-to-severe pediatric AD.REVIEWER COMMENTS:AD impacts up to a third of all children, and this study adds clarity to the discussion of how frequently these children should bathe to improve disease course. The authors’ takeaway is clear: bathing more frequently provides objective improvement in moderate-severe pediatric AD, and these effects are also recognized by caregivers. While therapy needs to be tailored to individual context, hydration is key and more frequent “soak-and-seal” is a cost-effective strategy.Copyright © 2020 by the American Academy of Pediatrics PreviousNext Back to top Advertising Disclaimer » In this issue Pediatrics Vol. 146, Issue Supplement 4 1 Dec 2020 Table of ContentsIndex by author View this article with LENS PreviousNext Email Article Thank you for your interest in spreading the word on American Academy of Pediatrics.NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. You are going to email the following Frequent Versus Infrequent Bathing in Pediatric Atopic Dermatitis: A Randomized Clinical Trial Message Subject (Your Name) has sent you a message from American Academy of Pediatrics Message Body (Your Name) thought you would like to see the American Academy of Pediatrics web site. Your Personal Message CAPTCHAThis question is for testing whether or not you are a human visitor and to prevent automated spam submissions. Request Permissions Article Alerts Log in You will be redirected to aap.org to login or to create your account. Or Sign In to Email Alerts with your Email Address Email * Citation Tools Frequent Versus Infrequent Bathing in Pediatric Atopic Dermatitis: A Randomized Clinical Trial Joseph M. Damron, Marcus Shaker Pediatrics Dec 2020, 146 (Supplement 4) S340; DOI: 10.1542/peds.2020-023861FF Citation Manager Formats BibTeXBookendsEasyBibEndNote (tagged)EndNote 8 (xml)MedlarsMendeleyPapersRefWorks TaggedRef ManagerRISZotero Share Frequent Versus Infrequent Bathing in Pediatric Atopic Dermatitis: A Randomized Clinical Trial Joseph M. Damron, Marcus Shaker Pediatrics Dec 2020, 146 (Supplement 4) S340; DOI: 10.1542/peds.2020-023861FF Share This Article: Copy Print Download PDF Insight Alerts Table of Contents Jump to section ArticlePURPOSE OF THE STUDY:STUDY POPULATION:METHODS:RESULTS:CONCLUSIONS:REVIEWER COMMENTS:Info & MetricsComments Related ArticlesNo related articles found.Google Scholar Cited By...No citing articles found.Google Scholar More in this TOC SectionAllergy Dog Ownership at 3 Months of Age is Associated With Protection Against Food Allergy Staphylococcus aureus Antibiotic Susceptibility Patterns in Pediatric Atopic Dermatitis Early-Life Exposure to Oral Antibiotics and Lung Function Into Early Adulthood Show more Allergy Allergic Skin Diseases Treatment Effect of Omalizumab on Severe Pediatric Atopic Dermatitis (the ADAPT Randomized Clinical Trial) Markers of Microbial Exposure Lower the Incidence of Atopic Dermatitis Ligelizumab for Chronic Spontaneous Urticaria Show more Allergic Skin Diseases Similar Articles Journal Info Editorial Board Editorial Policies Overview Licensing Information Authors/Reviewers Author Guidelines Submit My Manuscript Open Access Reviewer Guidelines Librarians Institutional Subscriptions Usage Stats Support Contact Us Subscribe Resources Media Kit About International Access Terms of Use Privacy Statement FAQ AAP.org shopAAP Follow American Academy of Pediatrics on Instagram Visit American Academy of Pediatrics on Facebook Follow American Academy of Pediatrics on Twitter Follow American Academy of Pediatrics on Youtube RSS © 2021 American Academy of Pediatrics