Study of some immunological indicators of interleukin-9 in Rheumatoid arthritis of Iraqi Patients

Abstract Rheumatoid arthritis is a chronic disease of the joints and passes through alternating stages of healing and relapse as it has genetic, clinical, pathological, and immunological characteristics. The present study was designed to evaluate the immunological status of some Iraqi patients with rheumatoid arthritis. The present study was conducted on a group of patients reviewed at Baquba Teaching Hospital / Consultation Clinic and from all districts of Diyala Province. For the period 2018-7-20 until 2019-2-1, Blood samples were collected from 50 patients with rheumatoid arthritis aged 29-75 years. On the other hand, 50 other blood samples from healthy individuals were collected as a control group, aged between 25 and 75 years. The study involved investigated the relationship between the immunological detection of the cellular motility of the IL-9 using ELIZA technique. The results of the present study showed that the percentage of female infection with rheumatoid arthritis was 94% higher than that of males by 6%. Also, the results recorded the highest incidence of rheumatoid arthritis in the 45-54 age group at the main of (369.12 ± 7.75) pg / ml and 38%, While the lowest recorded cases of the disease in the age group 65-75 years at the main (350.40 ± 10.73) pg / ml and by 16%. As, the results of the present study showed a significant increase in the level of the concentration of interleukin 9 in the serum of patients with rheumatoid arthritis (362.29 ± 26.86 pg / ml) compared to control group (332.45 ± 27.58) pg / ml at a probability level (P <0.01) Indicates a relationship between interleukin 9 and rheumatoid arthritis.