2020•New Journal of ChemistryRequires access

One-pot synthesis of 3-hydroxy-2-oxindoles via acyloin rearrangements of 2-hydroxy-indolin-3-ones generated in situ from 2-alkynyl arylazides

Zhiqiang Zhou, Yao Xu, Boyu Zhu, Ping Li, Guiwen Hu, Fan Yang, Shijie Xu, Xiaoxiang Zhang

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Abstract

A novel one-pot method to prepare 3-hydroxy-2-oxindoles via acyloin rearrangements of 2-hydroxy-indolin-3-ones generated in situ from 2-alkynyl arylazides has been described.

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A novel one-pot method to prepare 3-hydroxy-2-oxindoles via acyloin rearrangements of 2-hydroxy-indolin-3-ones generated in situ from 2-alkynyl arylazides has been described.

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Available abstract

A novel one-pot method to prepare 3-hydroxy-2-oxindoles via acyloin rearrangements of 2-hydroxy-indolin-3-ones generated in situ from 2-alkynyl arylazides has been described.

Key concepts: Chemistry, In situ, Combinatorial chemistry, Medicinal chemistry, Organic chemistry

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One-pot synthesis of 3-hydroxy-2-oxindoles via acyloin rearrangements of 2-hydroxy-indolin-3-ones generated in situ from 2-alkynyl arylazides — Research Paper | ScholarLens