One-pot synthesis of 3-hydroxy-2-oxindoles via acyloin rearrangements of 2-hydroxy-indolin-3-ones generated in situ from 2-alkynyl arylazides
Zhiqiang Zhou, Yao Xu, Boyu Zhu, Ping Li, Guiwen Hu, Fan Yang, Shijie Xu, Xiaoxiang Zhang
Abstract
Zhiqiang Zhou, Yao Xu, Boyu Zhu, Ping Li, Guiwen Hu, Fan Yang, Shijie Xu, Xiaoxiang Zhang
Abstract
A novel one-pot method to prepare 3-hydroxy-2-oxindoles via acyloin rearrangements of 2-hydroxy-indolin-3-ones generated in situ from 2-alkynyl arylazides has been described.
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A novel one-pot method to prepare 3-hydroxy-2-oxindoles via acyloin rearrangements of 2-hydroxy-indolin-3-ones generated in situ from 2-alkynyl arylazides has been described.
Key concepts: Chemistry, In situ, Combinatorial chemistry, Medicinal chemistry, Organic chemistry