IgA Nephropathies in Children: Epidemiological, Clinical, Histological and Evolutionary Profile: About 31 Cases

IgA nephropathy is one of the most common primary glomerulonephritis in children.It is characterized by the presence in the PBR of mesangial deposits of type A immunoglobulins.We report the clinical, biological, histopathological, therapeutic presentation and the evolution, through a retrospective study comprising 31 cases collected in the pediatric IV department of the children's hospital in Rabat from 2007 to 2017.31 cases have nephropathy in IgA, predominantly male.The average age of our patients at diagnosis was 10 years.Berger's disease was confirmed in 64% of cases, rheumatoid purpura in 30% of cases and 02 cases of secondary IgA nephropathy.Nephrotic proteinuria was present in 80% of cases, associated with hematuria (65%).Hypertension was present in 48% of patients while 32% of cases presented with acute renal failure.Lesions observed by light microscopy were according to the Oxford classification: M1 (61%), E1 (38%), S1 (41%), T1 + T2 (22%), C1 (22%).All the patients were put on corticosteroid therapy, associated with the immunosuppressant in 02 cases.The outcome was favorable for 93% of the patients and two patients progressed to CRF.