Field Trial of Intrauterine Antibiotic or Prostaglandin for Treatment of Clinical Endometritis in Dairy Cows

Endometritis is a localized inflammation and/or infection of the uterus characterized by sub-involution of the uterus, and associated with chronic bacterial uterine infection and purulent uterine discharge. Diagnosis and treatment of endometritis are a source of controversy, fueled by a lack of large-scale clinical trials with an objective case definition and economically meaningful outcomes. The objective of this study was to compare the effect on reproductive performance of two common approaches to the treatment of endometritis.