RISK FACTORS FOR PLASMODIUM KNOWLESI IN SOUTHEAST ASIA:A SYSTEMATIC REVIEW

Introduction: Plasmodium knowlesi zoonotic malaria has been identified in Borneo Malaysia in 2004, and has led to an increase in the number of cases throughout Southeast Asia. Many factors have contributed to increasing pattern. Therefore, this systematic review aims to identify risk factors for Plasmodium knowlesi infection that can aid in predicting and controlling the infection. Methods:Systematic search on articles related to risk factors of Plasmodium knowlesi infection was conducted using three databases namely PubMed, Scopus and Science direct. All the articles from year 2015 till May 2019 were selected. Results: A total of three articles were included in this review based on the study protocol. Three common risk factors for Plasmodium knowlesi infection was in identify mainly involved sociodemographic, work-related and behavioural factors. Conclusion: Risk factors for P. Knowlesi ranges not only from individual and community socidemographic background but also by environmental and geographical determinants. The inconsistency of the result was due to the variability and limitations of the studies itself. The research on P. Knowlesi, should be conducted with larger participants and longer length of follow up.