2011•N N Priorov Journal of Traumatology and OrthopedicsOpen access

Relation of Efficacy of Combined Use of Ibandronic Acid and Alfacalcidol with Bone Tissue Remodeling in Women with Postmenopausal Form of Osteoporosis

Svetlana Semenovna Rodionova, A A Elovoy-Vronskiy, Svetlana Semenovna Rodionova, A A Elovoy-Vronskiy

Abstract

Study of 51 female patients showed high efficacy of alfacalcidol (Alfa D3 - Teva) and ibandronic acid (Bonviva) combination for the treatment of postmenopausal form of systemic osteoporosis. Dependence of mineral bone density (MBD) on the primary intensity of bone tissue remodeling was observed. Assumption on the necessity of bone metabolism markers assessment at ibandronate use was confirmed. The fact that use of active form of vitamin D 3 eliminates such side effects of bisphosphonates as secondary hyperparathyroidism and hypocalcemia has been proved.

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Key concepts: Alfacalcidol, Bone remodeling, Medicine, Osteoporosis, Internal medicine, Bone mineral, Endocrinology, Secondary hyperparathyroidism