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2020•Bone ReportsOpen access

Enhanced BMP-2/BMP-4 ratio in patients with peripheral spondyloarthritis and in cytokine- and stretch-stimulated mouse chondrocytes

Anne Briolay, Alaeddine El Jamal, Paul Arnolfo, Benoît Le Goff, Frédéric Blanchard, David Magne, Carole Bougault

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Abstract

DTU-one osteometer.Reproductive ageing was estimated by collecting data on menstrual and reproductive history by questionnaires.Cellular ageing was estimated by X chromosome loss estimation (FISH probe).Data on actual health status, lifestyle factors (nutritional habits, habitual physical activity level) and the socioeconomic background of Roma families were collected by questionnaires.The results revealed that Roma women are prone to be more obese, to have higher amount of abdominal body fat, they have worse bone structure and experience longer reproductive period than the national reference values.The evaluation of cellular ageing estimation in Roma and non-Roma women is still in progress, the results of the analysis will be presented during the ECTS congress.This research was supported by the National Talent Programme of the Hungarian Ministry of Human Capacities (NTP-NFTÖ-19-B).

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DTU-one osteometer.Reproductive ageing was estimated by collecting data on menstrual and reproductive history by questionnaires.Cellular ageing was estimated by X chromosome loss estimation (FISH probe).Data on actual health status, lifestyle factors (nutritional habits, habitual physical activity level) and the socioeconomic background of Roma families were collected by questionnaires.The results revealed that Roma women are prone to be more obese, to have higher amount of abdominal body fat, they have worse bone structure and experience longer reproductive period than the national reference values.The evaluation of cellular ageing estimation in Roma and non-Roma women is still in progress, the results of the analysis will be presented during the ECTS congress.This research was supported by the National Talent Programme of the Hungarian Ministry of Human Capacities (NTP-NFTÖ-19-B).

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Available abstract

DTU-one osteometer.Reproductive ageing was estimated by collecting data on menstrual and reproductive history by questionnaires.Cellular ageing was estimated by X chromosome loss estimation (FISH probe).Data on actual health status, lifestyle factors (nutritional habits, habitual physical activity level) and the socioeconomic background of Roma families were collected by questionnaires.The results revealed that Roma women are prone to be more obese, to have higher amount of abdominal body fat, they have worse bone structure and experience longer reproductive period than the national reference values.The evaluation of cellular ageing estimation in Roma and non-Roma women is still in progress, the results of the analysis will be presented during the ECTS congress.This research was supported by the National Talent Programme of the Hungarian Ministry of Human Capacities (NTP-NFTÖ-19-B).

Key concepts: Bone morphogenetic protein 2, Cell biology, Bone morphogenetic protein 7, Cytokine, Peripheral, Bone morphogenetic protein, Chemistry, Medicine

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Enhanced BMP-2/BMP-4 ratio in patients with peripheral spondyloarthritis and in cytokine- and stretch-stimulated mouse chondrocytes — Research Paper | ScholarLens