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2020•Pharmacy managementRequires access

Gastro-oesophageal reflux disease: A pharmacist's perspective for 2020

Natalie Schellack, Gustav Schellack, Johanna Catharina Meyer, Lucille Malan, Quinten Labuschagne, Nazo Nxumalo, K. Kupa

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Abstract

Gastro-oesophageal reflux disease (GORD) is a medical disorder known and experienced by many, where the gastric contents of the stomach reflux into the distal part of the oesophagus. The incidence amongst members of the Western population is as high as 40%. The exact prevalence of GORD in South Africa is undetermined. Heartburn (dyspepsia) and/or acid regurgitation are common symptoms.1 GORD may be aggravated by various comorbidities and risk factors. GORD may be classified into three distinct classes, namely:2-4 The medical management of GORD is aimed at decreasing the amount of stomach acid that enters the distal oesophagus, usually by increasing the rate at which the stomach empties into Aggressive factors: • Acid • Pepsin • Bile

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What this paper is about

Gastro-oesophageal reflux disease (GORD) is a medical disorder known and experienced by many, where the gastric contents of the stomach reflux into the distal part of the oesophagus. The incidence amongst members of the Western population is as high as 40%. The exact prevalence of GORD in South Africa is undetermined. Heartburn (dyspepsia) and/or acid regurgitation are common symptoms.1 GORD may be aggravated by various comorbidities and risk factors. GORD may be classified into three distinct classes, namely:2-4 The medical management of GORD is aimed at decreasing the amount of stomach acid that enters the distal oesophagus, usually by increasing the rate at which the stomach empties into Aggressive factors: • Acid • Pepsin • Bile

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Available abstract

Gastro-oesophageal reflux disease (GORD) is a medical disorder known and experienced by many, where the gastric contents of the stomach reflux into the distal part of the oesophagus. The incidence amongst members of the Western population is as high as 40%. The exact prevalence of GORD in South Africa is undetermined. Heartburn (dyspepsia) and/or acid regurgitation are common symptoms.1 GORD may be aggravated by various comorbidities and risk factors. GORD may be classified into three distinct classes, namely:2-4 The medical management of GORD is aimed at decreasing the amount of stomach acid that enters the distal oesophagus, usually by increasing the rate at which the stomach empties into Aggressive factors: • Acid • Pepsin • Bile

Key concepts: Heartburn, Medicine, Reflux, Regurgitation (circulation), Gastroenterology, Internal medicine, Pepsin, Stomach

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