[Effects on learning and memory and mitochondrial energy metabolism in hippocampus of mice by subacute exposure to n-hexane].
Wei-Yan Zhao, T H Zhang, W L Wang, Bingfu Wang, Z Q Zhang, Lin Lu
Abstract
Wei-Yan Zhao, T H Zhang, W L Wang, Bingfu Wang, Z Q Zhang, Lin Lu
Abstract
Subacute exposure to n-hexane can result in the decrease of activities of mitochondrial respiratory chain enzyme complex in hippocampus of mice, which may lead to the disorder of mitochondrial energy metabolism by the decrease of ATPase activity and the imbalance of mitochondrial fusion-division, which must be one of the mechanisms of impairment of learning and memory of mice induced by n-hexane.
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Subacute exposure to n-hexane can result in the decrease of activities of mitochondrial respiratory chain enzyme complex in hippocampus of mice, which may lead to the disorder of mitochondrial energy metabolism by the decrease of ATPase activity and the imbalance of mitochondrial fusion-division, which must be one of the mechanisms of impairment of learning and memory of mice induced by n-hexane.
Key concepts: Chemistry, Hippocampus, FIS1, ATPase, Mitochondrion, Internal medicine, Endocrinology, mitochondrial fusion