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2020•Bioorganic & Medicinal ChemistryRequires access

Synthesis and evaluation of etoposide and podophyllotoxin analogs against topoisomerase IIα and HCT-116 cells

Matthew B. Murphy, Priyanka Kumar, Amber M. Bradley, Christopher E. Barton, Joseph E. Deweese, Susan L. Mercer

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Key concepts: Etoposide, Podophyllotoxin, Chemistry, Topoisomerase, Halogenation, Stereochemistry, Cell culture, Biochemistry

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Synthesis and evaluation of etoposide and podophyllotoxin analogs against topoisomerase IIα and HCT-116 cells — Research Paper | ScholarLens