[CD20-positive T cell lymphoma: clinicopathological features of five cases].
Shihong Shao, Yong‐Chang Wang, Xinrui Dai, Yujing Xiao, Jingjing Guan, Dongliang Lin, J G Wang, Y J Li, Xixin Xing, Peng Zhao
Abstract
Shihong Shao, Yong‐Chang Wang, Xinrui Dai, Yujing Xiao, Jingjing Guan, Dongliang Lin, J G Wang, Y J Li, Xixin Xing, Peng Zhao
Abstract
CD20-positive T-cell lymphoma is extremely rare. Its prognosis is closely related to the type of T-cell lymphoma, clinical stage and initial therapeutic effect. However, the expression of CD20 indicates the recurrence or progression of the disease, and the prognosis is relatively poor. When CD3 expression is absent in T-cell lymphoma, it is easy to be misdiagnosed as B-cell lymphoma. The combination of multiple immunohistochemical antibodies and molecular detection can improve the accuracy of diagnosis.
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CD20-positive T-cell lymphoma is extremely rare. Its prognosis is closely related to the type of T-cell lymphoma, clinical stage and initial therapeutic effect. However, the expression of CD20 indicates the recurrence or progression of the disease, and the prognosis is relatively poor. When CD3 expression is absent in T-cell lymphoma, it is easy to be misdiagnosed as B-cell lymphoma. The combination of multiple immunohistochemical antibodies and molecular detection can improve the accuracy of diagnosis.
Key concepts: CD20, Mycosis fungoides, Lymphoma, CD5, Medicine, Pathology, Gene rearrangement, Immunohistochemistry