Acute Kidney Injury
Abhinav Goyal, Parnaz Daneshpajouhnejad, Muhammad F. Hashmi, Khalid Bashir
Abstract
Abhinav Goyal, Parnaz Daneshpajouhnejad, Muhammad F. Hashmi, Khalid Bashir
Abstract
Acute kidney injury (AKI), previously called acute renal failure (ARF), denotes a sudden and often reversible reduction in the kidney function, as measured by glomerular filtration rate (GFR). Although, immediately after a renal insult, blood urea nitrogen (BUN) or creatinine levels may be within the normal range and the only sign of the acute kidney injury may be a decline in urine output. AKI can lead to the accumulation of water, sodium, and other metabolic products. It can also result in a number of electrolyte disturbances. It is a very common condition, especially among hospitalized patients. It can be seen in up to 7% of hospital admissions and 30% ICU admissions. There is no clear definition of AKI; however, several different criteria have been used in research studies such as RIFLE, AKIN (Acute Kidney Injury Network) and KDIGO (Kidney Disease: Improving Global Outcomes) criteria. Among these, KDIGO is the most recent and most commonly used tool. According to KDIGO, AKI is the presence of any of the following:
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Acute kidney injury (AKI), previously called acute renal failure (ARF), denotes a sudden and often reversible reduction in the kidney function, as measured by glomerular filtration rate (GFR). Although, immediately after a renal insult, blood urea nitrogen (BUN) or creatinine levels may be within the normal range and the only sign of the acute kidney injury may be a decline in urine output. AKI can lead to the accumulation of water, sodium, and other metabolic products. It can also result in a number of electrolyte disturbances. It is a very common condition, especially among hospitalized patients. It can be seen in up to 7% of hospital admissions and 30% ICU admissions. There is no clear definition of AKI; however, several different criteria have been used in research studies such as RIFLE, AKIN (Acute Kidney Injury Network) and KDIGO (Kidney Disease: Improving Global Outcomes) criteria. Among these, KDIGO is the most recent and most commonly used tool. According to KDIGO, AKI is the presence of any of the following:
Key concepts: Acute kidney injury, Renal function, Rifle, Medicine, Creatinine, Kidney disease, Kidney, Blood urea nitrogen