Quantitative Analysis of Fecal Hemoglobin Concentration in Colorectal Cancer Patients – The Values in the Screening and Diagnosis of Colorectal Cancer

Objective: To use immunochemical detection of fecal hemoglobin amount as a technical method, to perform a FIT test on the fecal specimens of research subjects who were going to undergo colonoscopy. The recorded results are compared and analyzed, and the sensitivity and specificity of the detection method in the diagnosis of colorectal cancer were evaluated. Methods: Three hundreds of individuals who were going to undergo colonoscopy were tested for GFOBT and FIT in feces in advance, and 20 ?g/g was used as the threshold for determining positive FIT result. The results were analyzed and compared with the results of colonoscopy. Results: The sensitivity of FIT to the diagnosis of colorectal cancer was 80.95%, and the specificity was 86.54%. The positive predictive values of FIT test in colorectal cancer screening were 53.1% and 81.77%, respectively. Conclusion: FIT is more sensitive and specific for detecting colorectal cancer and adenoma. The fecal occult blood test (FOBT) is stronger, and FIT test detection is more valuable in colon cancer screening.