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2020•Journal of Applied PhysiologyRequires access

Daily generation of a footward fluid shift attenuates ocular changes associated with head-down tilt bed rest

Justin S. Lawley, Gautam Babu, Sylvan L. J. E. Janssen, Lonnie G. Petersen, Christopher M. Hearon, Katrin A. Dias, Satyam Sarma, Michael A. Williams, Louis A. Whitworth, Benjamin D. Levine

Open publisher page 30 citations

Abstract

Choroid measurements appear to be sensitive to changes in gravitational gradients, as well as periods of head-down tilt (HDT) bed rest, suggesting that they are potential indicators of early ocular remodeling and could serve to evaluate the efficacy of countermeasures for SANS. Eight hours of lower body negative pressure (LBNP) daily attenuates the choroid expansion associated with 3 days of strict -6° HDT bed rest, indicating that LBNP may be an effective countermeasure for SANS.

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What this paper is about

Choroid measurements appear to be sensitive to changes in gravitational gradients, as well as periods of head-down tilt (HDT) bed rest, suggesting that they are potential indicators of early ocular remodeling and could serve to evaluate the efficacy of countermeasures for SANS. Eight hours of lower body negative pressure (LBNP) daily attenuates the choroid expansion associated with 3 days of strict -6° HDT bed rest, indicating that LBNP may be an effective countermeasure for SANS.

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Available abstract

Choroid measurements appear to be sensitive to changes in gravitational gradients, as well as periods of head-down tilt (HDT) bed rest, suggesting that they are potential indicators of early ocular remodeling and could serve to evaluate the efficacy of countermeasures for SANS. Eight hours of lower body negative pressure (LBNP) daily attenuates the choroid expansion associated with 3 days of strict -6° HDT bed rest, indicating that LBNP may be an effective countermeasure for SANS.

Key concepts: Bed rest, Head-Down Tilt, Medicine, Tilt (camera), Rest (music), Lower body, Body fluid, Choroid

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Daily generation of a footward fluid shift attenuates ocular changes associated with head-down tilt bed rest — Research Paper | ScholarLens