2020•PubMedOpen access

[Bisphosphonate-related osteonecrosis of the jaw caused by implant: a case report].

Wu Pingfan, Yu Li, Zhen-Ge Lei, Linlin Chen

Abstract

Osteonecrosis of the jaw could occur after intake of bisphosphonate drugs, which are widely used to treat osteoporosis and bone metastasis of malignant tumors. This effect has aroused concern among dentists. In this paper, a case of bisphosphonate-related osteonecrosis caused by implant is reported, and the pathogenesis, diagnosis, prevention, and treatment of bisphosphonate drug-induced osteonecrosis are described through a literature review. The effects of bisphosphonate drug treatment on dental implants are also discussed.

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Key concepts: Bisphosphonate, Osteonecrosis of the jaw, Medicine, Bisphosphonate-associated osteonecrosis of the jaw, Osteoporosis, Dentistry, Implant, Drug