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2020•Novel Approaches in Cancer StudyOpen access

The Role of Oxidative Stress in Cancer

Yi Wei Lu

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Abstract

Oxidative stress has increasingly been considered a factor in numerous diseases and cancers because of its extensive presence throughout the body. Reactive Oxygen Species (ROS), generated continuously from oxidative phosphorylation and received from various exogenous sources, are constantly used as a key molecule for signal transduction, but under conditions of oxidative stress, when they can no longer be suppressed, they have the potential to damage the cell’s DNA.

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Oxidative stress has increasingly been considered a factor in numerous diseases and cancers because of its extensive presence throughout the body. Reactive Oxygen Species (ROS), generated continuously from oxidative phosphorylation and received from various exogenous sources, are constantly used as a key molecule for signal transduction, but under conditions of oxidative stress, when they can no longer be suppressed, they have the potential to damage the cell’s DNA.

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Available abstract

Oxidative stress has increasingly been considered a factor in numerous diseases and cancers because of its extensive presence throughout the body. Reactive Oxygen Species (ROS), generated continuously from oxidative phosphorylation and received from various exogenous sources, are constantly used as a key molecule for signal transduction, but under conditions of oxidative stress, when they can no longer be suppressed, they have the potential to damage the cell’s DNA.

Key concepts: Oxidative stress, Reactive oxygen species, Oxidative phosphorylation, DNA damage, Signal transduction, Cell biology, Oxidative damage, DNA

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