2020•NatureOpen access

Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms

Christian B. Billesbølle, Caleigh M. Azumaya, Rachael C. Kretsch, Alexander S. Powers, Shane Gonen, Simon Schneider, Tara Arvedson, Ron O. Dror, Yifan Cheng, Aashish Manglik

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Key concepts: Hepcidin, Ferroportin, Chemistry, Internalization, Hemochromatosis, Biophysics, Cell biology, DMT1

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Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms — Research Paper | ScholarLens