2020PubMedOpen access

[A case report of Rosai-Dorfman disease with dyspnea].

Weifeng Chen, Shukun Liao, Ruiyun Xie, Lingyun You, Shaoping Peng, Ruiqing Wang

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Abstract

Rosai-Dorfman disease, also known as sinus histiocytosis with massive lymphadenopathy, is a kind of very rare idiopathic disease. The most common feature is the excessive accumulation of Langerhans cells in lymph nodes, but it may also occur in other areas and lead to related organ damage. We report a case of a 60-year-old man with Rosai-Dorfman disease, which led to dyspnea. Surgery is the best treatment to relieve the patient's dyspnea in a short time. Rosai-Dorfman disease has trend to self-healing, but in the case of special location, surgery should be selected. Some similar mass recurred in the operative area and bilateral nasal cavity in half a year after operation. Now we reviewed the relevant literatures and summarized the experience of diagnosis and treatment in Rosai-Dorfman disease.

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Rosai-Dorfman disease, also known as sinus histiocytosis with massive lymphadenopathy, is a kind of very rare idiopathic disease. The most common feature is the excessive accumulation of Langerhans cells in lymph nodes, but it may also occur in other areas and lead to related organ damage. We report a case of a 60-year-old man with Rosai-Dorfman disease, which led to dyspnea. Surgery is the best treatment to relieve the patient's dyspnea in a short time. Rosai-Dorfman disease has trend to self-healing, but in the case of special location, surgery should be selected. Some similar mass recurred in the operative area and bilateral nasal cavity in half a year after operation. Now we reviewed the relevant literatures and summarized the experience of diagnosis and treatment in Rosai-Dorfman disease.

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Available abstract

Rosai-Dorfman disease, also known as sinus histiocytosis with massive lymphadenopathy, is a kind of very rare idiopathic disease. The most common feature is the excessive accumulation of Langerhans cells in lymph nodes, but it may also occur in other areas and lead to related organ damage. We report a case of a 60-year-old man with Rosai-Dorfman disease, which led to dyspnea. Surgery is the best treatment to relieve the patient's dyspnea in a short time. Rosai-Dorfman disease has trend to self-healing, but in the case of special location, surgery should be selected. Some similar mass recurred in the operative area and bilateral nasal cavity in half a year after operation. Now we reviewed the relevant literatures and summarized the experience of diagnosis and treatment in Rosai-Dorfman disease.

Key concepts: Rosai–Dorfman disease, Sinus Histiocytosis with Massive Lymphadenopathy, Medicine, Disease, Histiocytosis, Surgery, Dermatology, Pathology

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[A case report of Rosai-Dorfman disease with dyspnea]. — Research Paper | ScholarLens