Synthesis of Pyrazole-Carboxamides and Pyrazole-Carboxylic Acids Derivatives: Simple Methods to Access Powerful Building Blocks
Byanca Silva Ferreira, Rafaela Corrêa Silva, Bernardo A. Souto, Maurício Silva dos Santos
Abstract
Byanca Silva Ferreira, Rafaela Corrêa Silva, Bernardo A. Souto, Maurício Silva dos Santos
Abstract
Abstract: Hybrid systems containing pyrazole moiety show a wide spectrum of biological activities. To access novel hybrids with pyrazole ring, in this work we synthesized twenty pyrazole-carboxylic acids and twenty pyrazole-carboxamides, using simple synthetic methods, to be used as building blocks in the development of new structures.
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Abstract: Hybrid systems containing pyrazole moiety show a wide spectrum of biological activities. To access novel hybrids with pyrazole ring, in this work we synthesized twenty pyrazole-carboxylic acids and twenty pyrazole-carboxamides, using simple synthetic methods, to be used as building blocks in the development of new structures.
Key concepts: Pyrazole, Chemistry, Moiety, Combinatorial chemistry, Simple (philosophy), Carboxylic acid, Ring (chemistry), Organic chemistry