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2020•Bioorganic & Medicinal ChemistryOpen access

Monoaryl derivatives as transthyretin fibril formation inhibitors: Design, synthesis, biological evaluation and structural analysis

Lidia Ciccone, Susanna Nencetti, Nicolò Tonali, Carole Fruchart‐Gaillard, William Shepard, Elisa Nuti, Caterina Camodeca, Armando Rossello, Elisabetta Orlandini

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Key concepts: Transthyretin, Chemistry, Tetramer, Fibrillogenesis, Diflunisal, Fibril, Amyloidosis, Amyloid (mycology)

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