2020Asian Journal of Chemical SciencesOpen access

Synthesis, Characterization and Antibacterial Evaluation of Mn (II), Co (II) and Cu (II) Complexes of Schiff Base Derived from 3-aminophenol and Benzaldehyde

Usman Abubakar Adamu, Buhari Magaji, Muhammad Nazifi Ibrahim, Mukhtar Muhammad Sani

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Abstract

Schiff base was prepared by the condensation of 3-aminophenol and benzaldehyde in a 1:1 ratio and its complexes of Mn(II), Co(II) and Cu(II) were synthesized in a 1:2 ratio (Metal: Ligand) and the Schiff base and the complexes were characterized by using the different techniques. The infrared spectral data revealed that the Schiff base behaved as a bidentate ligand and the molar conductivity value indicated that the complexes were non-electrolytes. Furthermore, the in vitro antibacterial activity of the Schiff base and its complexes was evaluated against one gram-negative and one gram-positive bacteria to indicate that Mn (II) complex demonstrated a good broad-spectrum activity against all the tested bacterial strains.

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Schiff base was prepared by the condensation of 3-aminophenol and benzaldehyde in a 1:1 ratio and its complexes of Mn(II), Co(II) and Cu(II) were synthesized in a 1:2 ratio (Metal: Ligand) and the Schiff base and the complexes were characterized by using the different techniques. The infrared spectral data revealed that the Schiff base behaved as a bidentate ligand and the molar conductivity value indicated that the complexes were non-electrolytes. Furthermore, the in vitro antibacterial activity of the Schiff base and its complexes was evaluated against one gram-negative and one gram-positive bacteria to indicate that Mn (II) complex demonstrated a good broad-spectrum activity against all the tested bacterial strains.

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Available abstract

Schiff base was prepared by the condensation of 3-aminophenol and benzaldehyde in a 1:1 ratio and its complexes of Mn(II), Co(II) and Cu(II) were synthesized in a 1:2 ratio (Metal: Ligand) and the Schiff base and the complexes were characterized by using the different techniques. The infrared spectral data revealed that the Schiff base behaved as a bidentate ligand and the molar conductivity value indicated that the complexes were non-electrolytes. Furthermore, the in vitro antibacterial activity of the Schiff base and its complexes was evaluated against one gram-negative and one gram-positive bacteria to indicate that Mn (II) complex demonstrated a good broad-spectrum activity against all the tested bacterial strains.

Key concepts: Schiff base, Benzaldehyde, Molar conductivity, Chemistry, Denticity, Ligand (biochemistry), Metal, Antibacterial activity

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Synthesis, Characterization and Antibacterial Evaluation of Mn (II), Co (II) and Cu (II) Complexes of Schiff Base Derived from 3-aminophenol and Benzaldehyde — Research Paper | ScholarLens