1978Biochemical JournalOpen access

Proteins from sciatic-nerve myelin in quaking and jimpy mice

J.-M. Matthieu

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Abstract

Myelin from two neurological mutants in mice was isolated from sciatic nerves and its protein composition analysed. In Quaking mice, two intrinsic myelin proteins P1 and P2 were drastically decreased, whereas the major myelin protein P0 was unaffected. A normal protein composition was found in sciatic myelin from Jimpy mice.

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Myelin from two neurological mutants in mice was isolated from sciatic nerves and its protein composition analysed. In Quaking mice, two intrinsic myelin proteins P1 and P2 were drastically decreased, whereas the major myelin protein P0 was unaffected. A normal protein composition was found in sciatic myelin from Jimpy mice.

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Available abstract

Myelin from two neurological mutants in mice was isolated from sciatic nerves and its protein composition analysed. In Quaking mice, two intrinsic myelin proteins P1 and P2 were drastically decreased, whereas the major myelin protein P0 was unaffected. A normal protein composition was found in sciatic myelin from Jimpy mice.

Key concepts: Myelin, Sciatic nerve, Myelin basic protein, Myelin sheath, Mutant, Anatomy, Chemistry, Biology

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Proteins from sciatic-nerve myelin in quaking and jimpy mice — Research Paper | ScholarLens