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Unprecedented Selectivities in the C7-Hydroxylation of Steroids Enabled by a P450-BM3 Mutant

Benjamin List, Benjamin Mitschke

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Abstract

Key words cytochrome P450-BM3 - C–H oxidation - steroid hydroxylation - directed evolution

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Key words cytochrome P450-BM3 - C–H oxidation - steroid hydroxylation - directed evolution

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Available abstract

Key words cytochrome P450-BM3 - C–H oxidation - steroid hydroxylation - directed evolution

Key concepts: Chemistry, Hydroxylation, Mutant, Stereochemistry, Organic chemistry, Biochemistry, Enzyme, Gene

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Unprecedented Selectivities in the C7-Hydroxylation of Steroids Enabled by a P450-BM3 Mutant — Research Paper | ScholarLens