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2020•American Journal of Biomedical Science & ResearchOpen access

Molecular basis of Antigenic Reassortment of Influenza Virus

Mohammed Helmy Faris Shalayel

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Abstract

Frequent pandemic alerts were raised by the World Health Organization in response to newly emerging influenza strains. This minireview highlights the dynamic alterations in the viral adaptability resulted from antigenic drift and reassortment that enable flu virus to escape recognition by the host immune system and neutralization by antibodies produced in preceding infections or vaccinations.

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What this paper is about

Frequent pandemic alerts were raised by the World Health Organization in response to newly emerging influenza strains. This minireview highlights the dynamic alterations in the viral adaptability resulted from antigenic drift and reassortment that enable flu virus to escape recognition by the host immune system and neutralization by antibodies produced in preceding infections or vaccinations.

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Available abstract

Frequent pandemic alerts were raised by the World Health Organization in response to newly emerging influenza strains. This minireview highlights the dynamic alterations in the viral adaptability resulted from antigenic drift and reassortment that enable flu virus to escape recognition by the host immune system and neutralization by antibodies produced in preceding infections or vaccinations.

Key concepts: Reassortment, Antigenic shift, Antigenic drift, Virology, Biology, Virus, Pandemic, Immune escape

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