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2020•Obstetrical & Gynecological SurveyRequires access

Systematic Analysis of Copy-Number Variations Associated With Early Pregnancy Loss

Y. Wang, Y. Li, Yiting Chen, Ruihao Zhou, Zi-Tong Sang, Lili Meng, J. Tan, Fei Qiao, Qi Bao, Di Xian Luo, Chieh Yu Peng, Y. S. Wang, Caihong Luo, Peng Cheng Hu, Zhouwei Xu

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Abstract

(Abstracted from Ultrasound Obstet Gynecol 2020;55:96–104) Early pregnancy loss is most commonly caused by embryonic numerical and structural chromosomal abnormalities, which explain more than 50% of miscarriages. In more recent years, submicroscopic copy-number variations (CNVs) have also been identified in some early miscarriage specimens.

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What this paper is about

(Abstracted from Ultrasound Obstet Gynecol 2020;55:96–104) Early pregnancy loss is most commonly caused by embryonic numerical and structural chromosomal abnormalities, which explain more than 50% of miscarriages. In more recent years, submicroscopic copy-number variations (CNVs) have also been identified in some early miscarriage specimens.

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Available abstract

(Abstracted from Ultrasound Obstet Gynecol 2020;55:96–104) Early pregnancy loss is most commonly caused by embryonic numerical and structural chromosomal abnormalities, which explain more than 50% of miscarriages. In more recent years, submicroscopic copy-number variations (CNVs) have also been identified in some early miscarriage specimens.

Key concepts: Miscarriage, Medicine, Early Pregnancy Loss, Pregnancy, Copy-number variation, Obstetrics, First trimester, Gynecology

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