Bir Ürtikerya Pigmentoza Olgusu

Abstract Mastocytosis is a disease group characterized by skin lesions and/or systemic involvement developing as a result of mast cell proliferation. The etiology is unknown. Ledby the skin it may involve bone marrow, bones, gastrointestinal system, liver, spleen andlymph glands. It is divided into two groups as cutaneous and systemic. Cutaneous mastocytosis are observed in childhood with the main types being urticaria pigmentosa, diffuse cutaneous mastocytosis and isolated mastocytoma. In mastocytosis, patients maybe observed to have itching, flushing, urticaria, abdominal pain, diarrhea and cardiovascular symptoms due to release of mast cell mediators. Urticaria pigmentosa (UP) is themost commonly seen cutaneous mastocytosis. Lesions are pink, red or brown in colorin the form of macules, papules and nodules. Generally, it occurs in the first six monthsof life and enters remission after puberty. Here we present the clinical and histopatho-logical findings of a six-month old male infant with UP diagnosis.