A COMPARATIVE STUDY OF INTUBATING CONDITIONS BETWEEN ROCURONIUM BROMIDE AND SUXAMETHONIUM FOR INTUBATION IN GENERAL ANAESTHESIA

AIMS: \nThis \nstudy \nwas \nconducted \nto \ncompare \nthe \nintubating \nconditions \nbetween \nRocuronium \nBromide \nand \nSuxamethonium \nfor \nendotracheal \nintubation \nin \nGeneral \nanaesthesia. \nMATERIALS \nAND \nMETHODS: \nIn \nthis \nprospective \nrandomized \ncontrolled \nstudy \n100 \npatients \nposted \nfor \ndifferent \nsurgeries \ndone \nunder \ngeneral \nanaesthesia \nwere \nincluded \nin \nthe \nstudy. \nThe \nfirst group \n– \nGroup I or Rocuronium (R) Group \nreceived \nInjection \nRocuronium \nBromide \nas \nthe \nmuscle \nrelaxant. \nThe second group \n- \nGroup II or Suxamethonium (S) group \nreceived \nInjection \nSuxamethonium \nas \nthe \nmuscle \nrelaxant. \nDescriptive \nstatistics \nthat \nincluded \nmean, \nstandard \ndeviation \n(SD), \nminimum \nand \nmaximum \nvalues \nwere \ncalculated \nfor \neach \nof \nthe \nt \nwo \nstudy \ngroups. \nThe \nstudent \n‘t’ \ntest \nwas \nused \nto \ndetermine \nwhether \nsignificant \ndifferences \nwere \npresent \nin \nthe \ndifferent \nvariables \nbetween \nthe \ntwo \nstudy \ngroups. \nThe \nchi \n- \nsquare \ntest \nwas \nalso \nused \nto \ndetermine \nsignificant \ndifferences \nin \nthe \nvarious \nconditions \nbetween \nthe \ngroups. \nSignificance \nfor \nall \nstatistical \ntests \nwas \npre \n- \ndetermined \nat \na \nprobability \nvalue \n(p \n- \nvalue) \nof \n0.05 \nor \nless. \nOnly \nthose \nvalues \nwhich \nare \nsignificant \nhave \nbeen \nmentioned. \nThe \npatient \nbelonging \nto \nGroup \nI \nreceived \nRocuronium \n1 \nmg/kg \nas \nthe \nmuscle \nrelaxant. \nThe \nsecond \ngroup \nwas \ndesignated \nas \nGroup \nII \nor \nSuxamethonium \ngroup. \nThese \npatients \nreceived \nInjection \nSuxamethonium \n1.5mg/kg \nas \nthe \nmuscle \nrelaxant. \nRESULTS: \nIn \nour \npresent \nstudy, \nwe \nhave \nused \n3.3xED \n95 \n(1mg/kg) \nof \nRocuronium \nbromide \nand \n1.5 \nmg/kg \nof \nSuxamethonium \nas \nthe \nintubating \ndose, \nproduced \ngood \nto \nexcellent \nintubating \nconditions \nat \n60 \nseconds \nas \nwell \nas \n90 \nseconds \nafter \nadministration. \nIntubating \nconditions \nfollowing \nSuxamethonium \n(1.5 \nmg/kg) \nwere \ncomparable \nwith \nthose \nafter \nRocuronium. \nCONCLUSION: \nRocuronium \nbromide \nin \na \ndose \nof \n1 \nmg/kg \ncan \nbe \nused \nas \nan \nalternative \nto \nSuxamethonium \n1.5 \nmg/kg \nprovided \nthe \nairway \nhas \nbeen \ncarefully \nassessed \nand \nno \ndifficulty \nis \nanticipated