Of dots and levels: a case of partial subacute combined degeneration
Divyani Garg, Jerry A George, Rajinder Kumar Dhamija
Abstract
Divyani Garg, Jerry A George, Rajinder Kumar Dhamija
Abstract
Subacute combined degeneration of the spinal cord is a typical clinical syndrome due to vitamin B12 deficiency, characterised by the involvement of the posterior column and corticospinal tracts. Occasionally, it may present with atypical features such as a sensory level and Lhermitte's sign, both traditionally considered to be a feature of compressive myelopathy. Spinal magnetic resonance imaging strongly augments the diagnosis by exhibiting changes in the posterior column in the form of a 'dot'. We describe such a patient who responded to therapy.
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Subacute combined degeneration of the spinal cord is a typical clinical syndrome due to vitamin B12 deficiency, characterised by the involvement of the posterior column and corticospinal tracts. Occasionally, it may present with atypical features such as a sensory level and Lhermitte's sign, both traditionally considered to be a feature of compressive myelopathy. Spinal magnetic resonance imaging strongly augments the diagnosis by exhibiting changes in the posterior column in the form of a 'dot'. We describe such a patient who responded to therapy.
Key concepts: Medicine, Posterior column, Subacute Combined Degeneration, Degeneration (medical), Myelopathy, Magnetic resonance imaging, Spinal cord, Vitamin B12