Embryological and Genetical Interpretations of Bilateral Polycystic Kidney Disease in a Neonate - A Case Report

Polycystic kidney disease is a rare developmental anomaly. It is inherited autosomal dominant or autosomal recessive. Autosomal recessive polycystic kidney disease (ARPKD), previously named infantile polycystic kidney disease. Clusters of cysts develop within the kidneys and fluid filled cysts displace normal renal tubules in this disease. This is characterized by cystic dilatation of the collecting ducts and progress to renal failure. We reported a case of Autosomal recessive polycystic kidney disease (ARPKD). Earlier antenatal ultrasonography had already detected the occurrence of polycystic kidney in fetus a day before delivery and it is confirmed after the parturition by fetal autopsy. The detailed study about the congenital anomalies of kidneys are significant for medical geneticists, embryologists, anatomists, pathologists, gynecologists, clinicians, urologists, transplant surgeons and radiologists.