A prospective comparative study to know the haemodynamic response of thiopentone, propofol and etomidate on laryngoscopy and intubation in adult patients posted for elective surgeries under general anaesthesia

Laryngoscopy and endotracheal intubation is the most commonly employed technique for the safe conduct of general anesthesia. However both laryngoscopy and intubation are noxious stimuli that are associated with hemodynamic responses in patients who are undergoing surgery under general anesthesia. Hence the present study is to know the hemodynamic response to laryngoscopy and intubation with different induction drugs which are used for general anesthesia. 90 patients of ASA class I and II, between 18-45yrs of age group, who were scheduled for various elective surgeries under general anesthesia were randomly divided into 3 groups of 30 each (n=30). Results: There was no much increase in the heart rate after induction and intubation (from 3rd minute onwards in group P and group T, (p statistically significant. The increase in MAP following induction and intubation was very minimal in group P when compared to group T and it was still more less when compared to group E, which was statiscally significant (P Conclusion: Propofol is acceptable as an induction agent with stable haemodynamics for laryngoscopy and intubation but, Etomidate is still a better choice for its haemodynamic stability over Propofol and Thiopentone. Keywords: Laryngoscopy, Endotracheal intubation, Thiopentone, Propofol, Etomidate.