Therapeutic selection of benign prostatic hyperplasia with lower urinary tract symptoms

Objective To improve therapeutic selection of benign prostatic hyperplasia ( BPH) with lower urinary tract symptoms (LUTS). Methods Two hundred and nine BPH patients with LUTS were divided into transurethral resection (group A,115 patients) and tamsulosin (group B,94 patients). The international prostate symptoms score (IPSS),quality of life (QOL),maximal flow rate (Qmax),international index of erectile function 5 (ITEF-5) and satisfactory degree were used for investigating safety and efficacy before and after the treatments. Results Mean follow-up periods were 15 months (ranged 10 to 22 months),all patients were followed up. IPSS,QOL and satisfactory degree between the two groups were no statistically significance after treatment. Qmax of group A was superior to group B [ (20.6 ± 2.8) ml/s vs (17.1 ±3.2) ml/s,P＜0.05],while IIEF-5 of group A was superior to group B [(19.3 ±3.4) scores vs (16.5 ±4.7) scores,P＜ 0.05]. Conclusions Therapeutic selections should be based on complete evaluations of patients symptoms and sexual status. Tamsulosin can improve both of the LUTS and sexual function,while transurethral resection of the prostate can relieve bladder outlet obstruction markedly but decrease patients' erectile function. Key words: Prostatic hyperplasia;  Sexual dysfunction,physiological;  Therapy;  Lower urinary tract symptoms;  Transurethral resection